赵静-导师简介

一、个人情况介绍

赵静，女，1984年12月生，博士，苏北人民医院药学部副研究员，江苏省第六期“333工程”培养对象，《Journal of Geriatric Cardiology》青年编委，研究方向：心血管药理学与临床药学。

二、代表性成果

（1）代表性论文

1. Zhao J, Gao JL, Zhu JX, Zhu HB, Peng X, Jiang M, Fu Y, Xu J, Mao XH, Hu N, Ma MH, Dong DL*. The different response of cardiomyocytes and cardiac fibroblasts to mitochondria inhibition and the underlying role of STAT3. Basic Res Cardiol. 2019;114(2):12.

2. Hang PZ, Ge FQ, Zhang MR, Li QH, Yu HQ, Song YC, Guo DD, Zhao J*, Zhu H*. BDNF mimetic 7,8-dihydroxyflavone rescues rotenone-induced cytotoxicity in cardiomyocytes by ameliorating mitochondrial dysfunction. Free Radic Biol Med. 2023;198:83-91.

3. Hang PZ, Liu J, Wang JP, Li FF, Li PF, Kong QN, Shi J, Ji HY, Du ZM*, Zhao J*. 7,8-Dihydroxyflavone alleviates cardiac fibrosis by restoring circadian signals via downregulating Bmal1/Akt pathway. Eur J Pharmacol. 2023;938:175420.

4. Hang PZ, Li PF, Liu J, Li FF, Chen TT, Pan Y, Zhang MR, Yu HQ, Ji HY, Du ZM*, Zhao J*. Small-molecule 7,8-dihydroxyflavone counteracts compensated and decompensated  cardiac hypertrophy via AMPK activation. J Geriatr Cardiol. 2022;19(11):853-866.

5. Zhao J, Li P, Zhu H, Ge FQ, Liu J, Xia JJ*, Hang PZ*. 7,8-Dihydroxyflavone suppresses the proliferation and induces apoptosis of human osteosarcoma cells. Acta Biochimica et Biophysica Sinica. 2021;53(7)903-911.

（2）主持课题

1. 国家自然科学基金面上项目，酪氨酸激酶受体B调控Rev-erb/Bmal1/P300生物钟基因网络抑制心肌纤维化的分子机制, 2021.1-2024.12。

2. 国家自然科学基金面上项目，心梗后心衰治疗的新靶点--溶酶体跨膜蛋白175，2024.1-2027.12。

三、联系方式

zhaojinghmu@163.com