一、个人情况简介
1984.10生，中西医结合基础博士，大连医科大学药学院 药物分析教研室 副教授
大连市药学会 药物分析专业委员会 委员
Traditional Medicine Research, Journal of Aging Science杂志编委
研究方向：中药药效物质基础及生物活性研究
二、代表性成果
文章：
1. Lianhong Yin, Meng Gao, Lina Xu, Yan Qi, Lan Han, Jinyong Peng *. Single-cell analysis of cellular heterogeneity and interactions in the ischemia-reperfusion injured mouse intestine. Journal of Pharmaceutical Analysis, 13(2023): 760-775. (第一作者) SCI, Q1
2. Zhe Zhang, Xuerong Zhao, Meng Gao, Lina Xu, Yan Qi, Jinhong Wang * and Lianhong Yin*. Dioscin alleviates myocardial infarction injury via regulating BMP4/NOX1-mediated oxidative stress and inflammation. Phytomedicine. 2022103:154222 (通讯作者) SCI, Q1C
3. Li R; Qi Y; Yuan Q; Xu L; Gao M; Xu Y; Han X; Yin L#; Liu C#. Protective effects of dioscin against isoproterenol-induced cardiac hypertrophy via adjusting PKCepsilon/ERK-mediated oxidative stress. Eur J Pharmacol. 2021, 907: 174,277. (通讯作者) SCI, Q2
4. Dong L#; Yin L#; Li R; Xu L; Xu Y; Han X; Qi Y. Dioscin alleviates lung ischemia/reperfusion injury by regulating FXR-mediated oxidative stress, apoptosis, and inflammation. Eur J Pharmacol. 2021, 908: 174321. (第一作者) SCI, Q2
5. Xuerong Zhao#, Lianhong Yin#, Lingling Fang, Lina Xu, Pengyuan Sun, Ming Xu, Kexin Liu, Jinyong Peng*. Protective effects of dioscin against systemic inflammatory response syndromevia adjusting TLR2/MyD88/NF_ κb signal pathway. International Immunopharmalogy, 2018, 65: 458-469. (第一作者) SCI, Q2
6. Yin Lianhong, Qi Yan, Xu Youwei, Xu Lina, Han Xu, Tao Xufeng, Song Shasha, Peng Jinyong. Dioscin Inhibits HSC-T6 Cell Migration via Adjusting SDC-4 Expression: Insights from iTRAQ-Based Quantitative Proteomics. Frontiers in Pharmacology, 2017, 8: 665. (第一作者) SCI, Q1C
7. Yin L#, Zheng L#, Xu L, Dong D, Han X, Qi Y, Zhao Y, Xu Y, Peng J*. In-silico prediction of drug targets, biological activities, signal pathways and regulating networks of dioscin based on bioinformatics. BMC Complementary and Alternative Medicine. 2015, 15:41 (第一作者), SCI, Q1D
8. Yin L, Sun CK, Han X, Xu L, Xu Y, Qi Y, Peng J. Preparative purification of bromelain (EC 3.4.22.33) from pineapple fruit by high-speed counter-current chromatography using a reverse-micelle solvent system. Food Chemistry. 2011; 129 (3): 925-932. (第一作者) SCI, Q1
9. Yin L, Sun CK, Han X, Xu L, Xu Y, Qi Y, Peng J. Preparative purification of bromelain (EC 3.4.22.33) from pineapple fruit by high-speed counter-current chromatography using a reverse-micelle solvent system. Food Chemistry. 2011; 129 (3): 925-932. (第一作者) SCI, Q1
10. Yin L, Xu L, Yu K, Zhen Y, Han X, Xu Y, Qi Y, Peng J, Tan A. Orthogonal test design for optimization of suitable conditions to separate C-phycocyanin from Spirulina platensis by high-speed counter-current chromatography using reverse micelle solvent system. Journal of Separation Science. 2011; 34 (11): 1253-1260. (第一作者) SCI, Q2
11. Yin, LH; Xu, LN; Han, X; Xu, YW; Qi, Y; Peng, JY. Determination of Poricoic Acid A in Rat Plasma after Oral and Intravenous Administration by LC-MS-MS and Its Application to a Pharmacokinetic Study. Chromatographia. 2010; 72 (5-6): 465-472. (第一作者) SCI, Q3
12. Yin, Lian-Hong; Xu, Li-Na; Wang, Xiao-Na; Lu, Bi-Nan; Liu, Yue-Tao; Peng, Jin-Yong. An Economical Method for Isolation of Dioscin from Dioscorea nipponica Makino by HSCCC Coupled with ELSD, and a Computer-Aided UNIFAC Mathematical Model. Chromatographia. 2010; 71 (1-2): 15-23. (第一作者) SCI, Q3
13. Yin, Lianhong; Li, Yingnan; Lu, Binan; Jia, Yujie; Peng, Jinyong. Trends in Counter-Current Chromatography: Applications to Natural Products Purification. Separation and Purification Reviews. 2010; 39 (1-2): 33-62. (第一作者) SCI, Q1
14. Lianhong Yin，Youwei Xu，Yan Qi，Xu Han，Lina Xu，Jinyong Peng，C.K. Sun. A green and efficient protocol for industrial-scale preparation of dioscin from Dioscorea nipponica Makino by two-step macroporous resin column chromatography. Chemical Engineering Journal, 2010; 165 (1): 281-289. (第一作者) SCI, Q1
课题：
1. 国家自然科学基金青年科学基金项目，81603178，薯蓣皂苷对顺铂诱导肾损伤的保护作用及调控miR-34a/Sirt1信号通路的分子机制研究，2017/01-2019/12，17.3万元，已结题、主持。
2. 辽宁省科技计划一般项目，L2013352、中药金樱子中保肝作用物质基础及分子机制研究、2013.01-2015.12、3万元、已结题、主持。
三、联系方式
E-mail：yinlianhong1015@163.com
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