
一、个人情况介绍
冯磊,1988年出生,研究员,博士生导师,主要从事酶活性荧光识别体系的构建及其在中药中的应用研究。国家级青年科技人才,辽宁省“兴辽英才计划”青年拔尖人才,中华中医药学会青年人才托举工程项目A类、辽宁省自然科学基金优秀青年基金、大连市优秀青年科技基金获得者,大连市青年科技之星。主持国家自然科学基金面上项目、青年基金、辽宁省自然科学基金面上项目。近5年,发表SCI论文40余篇,获辽宁省2023年度科技进步奖二等奖一项(第一完成人),发表英文专著Imaging Tools for Chemical Biology一部。
二、代表性成果
1. Rational Molecular Design of a Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2D6, Angewandte Chemie International Edition, 2024, 63, e202409217.
2. Rational design of a two-photon fluorescent probe for human cytochrome P450 3A and the visualization of mechanism-based inactivation, Angewandte Chemie International Edition, 2022, 61, e202113191.(Hot paper, IF=16.6)
3. A molecular-splicing strategy for constructing a near-infrared fluorescent probe for UDP-glucuronosyltransferase1A1, Angewandte Chemie International Edition, 2021, 60, 24566–24572.(Hot paper, IF=16.6)
4. A NIR fluorescent probe for Vanin-1 and its applications in imaging, kidney injury diagnosis, and the development of inhibitor, Acta Pharmaceutica Sinica B, 2022, 12, 316-325 (IF=14.5,ESI高被引)
5. A practical strategy to develop isoform-selective near-infrared fluorescent probes for human cytochrome P450 enzymes, Acta Pharmaceutica Sinica B, 2022, 12(4):1976-1986 (IF=14.5)
三、联系方式
招生专业:
学术博士:中西医结合基础;学术硕士:药理学
联系方式:leifeng@dmu.edu.cn