王晗-专业学位

王晗，1986年10月生，博士研究生、副主任药师、硕士生导师。现任大连医科大学附属第二医院临床药学教研室副主任，中国药学会《中国临床药理学杂志》首届千人新苗青年委员会一区委员，大连市药学会科技创新青年药学工作者。以第一作者身份发表SCI论文5篇，主持国自然青年、博士后面上项目等省、市级科研项目共4项。

研究方向：

1、 调控病毒--宿主细胞识别的新型抗流感药物先导化合物的发现

2、 肿瘤耐药机制研究，开发具有化疗增敏活性的候选药物

3、 器官移植药物临床合理应用

代表性成果：

1. Selective and facile deacetylation of pentacycilic triterpenoid under methanolic ammonia condition and unambiguous NMR analysis, Chinese Chemical Letters, 31 (2020) 333-336.

2. Significance of tumor-associated autoanitibodies in the early diagnosis of lung cancer, The Clinical Respiratory Journal, 12 (2018) 2020-2028.

3. Design, synthesis and biological evaluation of novel L-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors, European Journal of Medicinal Chemistry, 110 (2016) 376-388.

4. Synthesis and biological evaluation of ring A and/or C expansion and opening echinocysit acid derivatives for anti-HCV entry inhibitors, European Journal of Medicinal Chemistry, 102 (2015) 594-599.

5. Elucidation of the pharmacophore of echinocystic acid, a new lead for blocking HCV entry, European Journal of Medicinal Chemistry, 64 (2013) 160-168.

邮箱: wanghan_phd@126.com